This indicates an attack attempt to exploit a remote Denial of Service attack on LANDesk Management Agent software.
The vulnerability is due to an improper out-of-bounds memory read exception handling when parsing a crafted HTTP request sent to remote control server application issuser.exe. A remote attacker could exploit this to terminate the target application.
LANDesk Agent 220.127.116.111 and below
System Compromise: Remote attackers can cause denial of service on the vulnerable machine
Currently we are unaware of any vendor supplied patch or updates available for this issue.