This indicates an attack attempt to exploit a Directory Traversal vulnerability in Oracle's Application Testing Suite.
The vulnerability is caused by improper validation of user supplied data when the vulnerable application handles a maliciously crafted request. An attacker can exploit this to execute arbitrary code in the context of the vulnerable application via a crafted request.
Oracle Application Testing Suite 220.127.116.11
Oracle Application Testing Suite 18.104.22.168
System Compromise: Remote attackers can gain control of vulnerable systems
Apply the most recent upgrade or patch from the vendor